CHPOP Prep Course (CHPOP): free quiz

1. Question 1 of 10

   A CHPOP candidate is assisting a pharmacist with order review. A fictional 78-year-old patient has apixaban 5 mg by mouth twice daily for atrial fibrillation and a new clarithromycin 500 mg by mouth twice daily for 7 days; estimated CrCl is 24 mL/min. Within CHPOP role boundaries, what is the best next step?

   Choose one answer

   AFlag the renal function and CYP3A4/P-gp interaction concern, then escalate to the supervising pharmacist before dispensing.BProceed with apixaban 5 mg by mouth twice daily because clarithromycin is only a short course and counseling can address bleeding risk.CRecommend changing apixaban to 2.5 mg by mouth twice daily and document the dose change without pharmacist review.DSubstitute rivaroxaban 15 mg by mouth once daily because it is a renal-adjusted anticoagulant option for atrial fibrillation.
2. Question 2 of 10A pharmacist-scope CHPOP candidate reviews a practice item about apixaban 5 mg by mouth twice daily for atrial fibrillation in a patient also taking diltiazem 240 mg by mouth daily. The candidate missed it because renal dosing, interaction screening, and documentation terms were mixed across domains. The CHPOP outline gives domains but no item weights. Which study structure best follows domain-based blueprint logic?
   Choose one answer

   AStudy only anticoagulant dosing tables until apixaban dose-reduction criteria are memorized, then resume mixed practice questions.BPrioritize drug-interaction questions involving diltiazem because CYP3A4/P-glycoprotein inhibition is the likely single discriminator in apixaban cases.CCreate broad domain folders, map terms, rules, scenarios, and calculations into each folder, and review weak domains with uniform coverage unless weighting is stated.DUse renal-adjustment questions as the organizing framework and place documentation, ethics, and workflow content under renal dosing if they appeared in the same item.
3. Question 3 of 10

   An ambulatory-care pharmacist reviews a new prescription for nirmatrelvir/ritonavir 300 mg/100 mg by mouth twice daily for 5 days. The patient takes apixaban 5 mg by mouth twice daily for atrial fibrillation, and estimated CrCl is 72 mL/min. Using the Task-Fact-Rule-Action framework, which action best fits the pharmacist’s scope?

   Choose one answer

   ARecommend rivaroxaban 10 mg by mouth once daily during the 5-day antiviral course.BDispense both medications unchanged and counsel the patient to report bruising.CClarify with the prescriber about temporarily reducing apixaban to 2.5 mg by mouth twice daily during ritonavir exposure, consistent with labeling and local protocol.DHold apixaban for 5 days without contacting the prescriber because renal function is normal.
4. Question 4 of 10

   While verifying nirmatrelvir/ritonavir 300 mg/100 mg by mouth twice daily for 5 days for a fictional patient, a CHPOP candidate working under pharmacist supervision sees eGFR 45 mL/min and simvastatin 40 mg nightly. The prescriber is unavailable for 20 minutes; a technician suggests telling the patient you are the pharmacist and dispensing the standard dose. Which action best applies professional ethics principles?

   Choose one answer

   A

   Dispense nirmatrelvir/ritonavir 300 mg/100 mg twice daily and advise continuing simvastatin because the antiviral course is short.

   B

   Dispense nirmatrelvir/ritonavir 150 mg/100 mg twice daily for renal adjustment, but defer the simvastatin issue until follow-up.

   C

   State your correct role, hold and clarify the order with the supervising pharmacist or prescriber, and address both renal dose reduction and simvastatin management.

   D

   Substitute molnupiravir 800 mg twice daily without prescriber authorization to avoid the renal adjustment and interaction concerns.

5. Question 5 of 10

   In a community pharmacy, a pharmacist is reviewing warfarin 5 mg by mouth once daily for fictional patient Daniel Reed. A caller claiming to be Daniel’s employer asks whether Daniel picked up the prescription and whether he is taking it correctly. Within pharmacist-scope confidentiality practice, what is the best response?

   Choose one answer

   ADecline to disclose information until the caller’s identity and legal authority or Daniel’s authorization are verified, then share only the minimum necessary information.BProvide the dose and pickup date but omit the diagnosis because dosing information is not protected health information.CDiscuss Daniel’s full medication profile to prevent warfarin interactions, including any antibiotics or amiodarone.DConfirm only that warfarin was dispensed because adherence affects workplace safety.
6. Question 6 of 10

   As a CHPOP candidate supporting pharmacist-scope medication reconciliation, you review discharge documentation for apixaban 5 mg by mouth twice daily for atrial fibrillation. The patient is 82 years old, weighs 58 kg, has SCr 1.1 mg/dL, and takes verapamil ER 240 mg by mouth daily. The prescriber confirms changing apixaban to 2.5 mg by mouth twice daily. Which documentation entry best meets objective documentation standards?

   Choose one answer

   A

   “No change needed to apixaban 5 mg PO BID because SCr is below 1.5 mg/dL; patient appears clinically stable.”

   B

   “Changed apixaban to 2.5 mg PO BID because verapamil ER 240 mg daily requires automatic dose reduction with all DOAC therapy.”

   C

   “Prescriber wrote an unsafe apixaban 5 mg BID order and nearly caused harm; corrected after pharmacy caught the mistake.”

   D

   “09:20: Reviewed apixaban 5 mg PO BID profile; age 82 and weight 58 kg meet dose-reduction criteria. Verapamil ER 240 mg daily noted. Dr. Lee confirmed apixaban 2.5 mg PO BID; discharge list updated per policy.”

7. Question 7 of 10

   A CHPOP candidate is reviewing a community pharmacy near miss. A patient taking clarithromycin 500 mg by mouth twice daily for 7 days and having serum creatinine suggesting reduced renal function was about to receive apixaban 5 mg by mouth twice daily for atrial fibrillation. The technician caught the interaction before dispensing and asks what safety-culture response best supports the pharmacist’s scope and safer systems.

   Choose one answer

   AChange the order to rivaroxaban 20 mg by mouth daily without contacting the prescriber because it is another direct oral anticoagulant.BProceed with apixaban 5 mg by mouth twice daily because the error did not reach the patient, then remind staff to work faster next time.CDispense apixaban 2.5 mg by mouth twice daily automatically because reduced renal function often requires a lower dose.DPause dispensing, involve the pharmacist to assess the clarithromycin interaction and renal dosing, document the near miss according to policy, and use it for system learning.
8. Question 8 of 10During pharmacist verification, an order for metformin ER 1,000 mg PO twice daily is entered for a patient with eGFR 22 mL/min/1.73 m² and a contrast CT scheduled today. The technician’s queue held the prescription, and no medication was dispensed or administered. As the pharmacist, which factual event type and reporting action best fits this situation, recognizing local reporting thresholds may vary?
   Choose one answer

   AClassify it as a medication incident because metformin was contraindicated, then dispense a reduced dose such as metformin ER 500 mg PO daily.BClassify it as a near miss because the unsafe metformin order was intercepted before reaching the patient, and report it according to local policy.CClassify it only as an unsafe condition because renal-dose and contrast-related alerts were inadequate, with no event report needed.DClassify it as routine therapy optimization and independently substitute another oral agent, such as sitagliptin 100 mg PO daily.
9. Question 9 of 10

   A pharmacist is verifying apixaban 5 mg by mouth twice daily for stroke prevention in an 82-year-old patient weighing 58 kg. The profile also shows ketoconazole 400 mg by mouth daily, and the current serum creatinine is missing. Using risk severity factors, what is the most appropriate next step before dispensing?

   Choose one answer

   A

   Dispense apixaban 5 mg twice daily and schedule routine follow-up because the ordered dose is standard for many adults.

   B

   Recommend rivaroxaban 20 mg once daily instead because it avoids apixaban’s twice-daily dosing complexity.

   C

   Hold dispensing and clarify with the prescriber, citing high bleeding severity from age, low weight, missing renal data, and ketoconazole interaction.

   D

   Change the prescription to apixaban 2.5 mg twice daily and dispense because age and weight meet dose-reduction criteria.

10. Question 10 of 10

    A pharmacy receives a new e-prescription for apixaban 5 mg by mouth twice daily for atrial fibrillation. The patient profile shows ketoconazole 400 mg by mouth daily and CrCl 24 mL/min. As a CHPOP candidate supporting pharmacist-scope workflow, which next step best follows standard intake, verification, processing, and completion sequencing?

    Choose one answer

    ARoute the order to pharmacist verification before processing because renal function and a strong CYP3A4/P-gp inhibitor require clinical review.BCancel the prescription at intake because apixaban cannot be dispensed with renal impairment.CProcess and fill the prescription, leaving the interaction for counseling at completion.DChange the prescription to apixaban 2.5 mg by mouth twice daily and continue normal processing.

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