Free practice quiz
CRAS Prep Course (CRAS): free quiz
10 questions from the program. See your score right away, then unlock the explanation of every answer.
- Question 1 of 10
During pharmacist-supervised medication reconciliation, a patient reports apixaban 5 mg by mouth twice daily for atrial fibrillation and newly prescribed clarithromycin 500 mg by mouth twice daily. The CRAS protocol says medication interactions or unclear anticoagulant orders must be documented and escalated, not independently changed. What is the most appropriate CRAS-level action?
Role-boundary decision
B is correct. Clarithromycin inhibits CYP3A4/P-gp and may increase apixaban exposure; a CRAS documents and escalates rather than adjusts anticoagulation. C is tempting because dose reduction may be considered in some interaction contexts, but changing anticoagulant dose is prescribing-level judgment. A ignores a clinically relevant interaction flag. D is tempting because rivaroxaban is another DOAC, but selecting an alternative anticoagulant is outside CRAS scope and still requires interaction/renal review.
NOTICE: DOAC plus CYP3A4/P-gp inhibitor. SAY: report exact drugs/doses. MONITOR: bleeding signs per protocol. HOLD/CLARIFY/ESCALATE: unclear or interacting anticoagulant order. - Question 2 of 10
A CRAS working under a pharmacist-approved dispensing protocol reviews apixaban 5 mg by mouth twice daily for atrial fibrillation. The medication profile also lists ketoconazole 400 mg by mouth daily. The protocol states: “Immediate: verify interacting medications and report strong CYP3A4/P-gp inhibitors before dispensing.” Which response best identifies the task cue and required action?
Task cue
D is correct: “immediate,” “verify,” and “report” signal safety escalation, not routine documentation or calculation. Apixaban is a factor Xa inhibitor; ketoconazole strongly inhibits CYP3A4/P-gp and can increase apixaban exposure. C is tempting because the dose is standard, but it ignores the interaction cue. A is tempting because apixaban has dose-reduction rules, but CRAS should not independently adjust therapy. B is tempting because rivaroxaban is a related DOAC, but switching is outside CRAS scope and may not solve interaction risk.
NOTICE ketoconazole; SAY interaction needs review; MONITOR bleeding signs per protocol; HOLD/CLARIFY/ESCALATE before dispensing. - Question 3 of 10
A CRAS candidate is reviewing a pharmacist-supervised practice case: warfarin 5 mg by mouth once daily. The study note asks the candidate to verify that yesterday’s INR value, dose, prescriber callback time, and patient education handout were entered in the correct record fields per protocol. Which inferred study domain best labels this review task?
Review Inferred Domain Mapping
A is correct: the key issue is complete, accurate record entry, not independent warfarin management. B is tempting because INR and warfarin are terms, but vocabulary is not the main task. D is tempting because protocol is mentioned, but no sequence is being selected. C is tempting because anticoagulation may be high risk, but no competing urgent task is presented.
NOTICE missing fields; SAY you are reconciling the record; MONITOR completion before sign-off; HOLD/CLARIFY/ESCALATE if data conflict or required entries are absent. - Question 4 of 10
During medication reconciliation under pharmacist-approved workflow, a CRAS candidate reviews a patient taking metformin 500 mg by mouth twice daily. The patient says, “I feel dizzy,” and the measured blood pressure is 88/54 mm Hg. Which documentation best uses common clinical terminology by separating subjective report from objective finding?
C is correct: “Reports dizziness” is subjective; the measured blood pressure is objective and factual. D is tempting because it links symptom and drug, but causation is unsupported. A uses interpretation and implies a treatment decision outside CRAS scope. B is a medication-therapy conclusion; metformin is not typically a direct hypotension cause, and discontinuation requires pharmacist/prescriber review. Document neutral facts and escalate abnormal findings per protocol.
- Question 5 of 10
In a pharmacist-supervised medication reconciliation workflow, an order reads: warfarin 2.5 mg by mouth once daily. Available tablets are warfarin 5 mg. The patient also reports taking trimethoprim-sulfamethoxazole 160/800 mg by mouth twice daily. Which CRAS documentation entry is safest before pharmacist review?
A is correct. Warfarin has narrow therapeutic index PK/PD; 2.5 mg from a 5 mg tablet equals 0.5 tablet, and a leading zero improves decimal safety. Trimethoprim-sulfamethoxazole can increase warfarin effect and INR, requiring pharmacist clarification. B is tempting because the tablet fraction is right, but “.5” omits the leading zero and misses the interaction. D has the right conversion, but “2.50 mg” uses an unsafe trailing zero and delays interaction review. C flags the interaction, but misplaces the decimal: 0.25 mg is one-tenth the ordered dose. Pharmacist Action: NOTICE warfarin plus TMP-SMX; SAY dose conversion; MONITOR INR/bleeding per protocol; HOLD/CLARIFY/ESCALATE unclear decimals or interacting therapy.
- Question 6 of 10
In a clinic pharmacy workflow, a CRAS candidate supporting the pharmacist reviews an electronic medication order for fictional patient Mara Lee: apixaban 5 mg by mouth twice daily, entered today. The chart shows the drug, dose, route, frequency, and patient name, but no second patient identifier and no prescriber signature/authentication. Under record-component protocol, what is the best next step before filing the order?
Record Components
B is correct: PK/PD details for apixaban 5 mg PO twice daily do not validate an order without two identifiers and prescriber authentication. C is tempting because dosing fields are complete, but missing identifiers/signature can invalidate the entry. D is a renal-dose trap: rivaroxaban dosing is plausible, but a CRAS/pharmacy-support role must not substitute anticoagulants. A is an interaction trap: amiodarone review matters, but it does not cure an unauthenticated record. Review Record Components — focus on identifier and signature requirements.
NOTICE missing identifier/signature; SAY clarification is needed; MONITOR corrected order before filing; HOLD/CLARIFY/ESCALATE until authenticated. - Question 7 of 10
A CRAS candidate in an outpatient infusion area is asked, within protocol, to help prepare a station before a nurse administers cefazolin 1 g IV every 8 hours. After touching a shared workstation and before entering the patient care area, the candidate plans to put on clean gloves. What is the best next step?
Hand hygiene before gloves
C is correct: hand hygiene is required before donning gloves and before patient-area tasks; gloves are an added barrier, not a substitute. A is tempting because gloves reduce contamination, but they do not replace hand hygiene. D is tempting as a “double step,” but alcohol rub is for hands, not routine glove decontamination. B misses the required workflow point before potential patient-area exposure.
Pharmacist Action: NOTICE shared-surface contact; SAY you will clean hands before gloves; MONITOR compliance each room entry; HOLD/CLARIFY/ESCALATE repeated missed hygiene or unclear local protocol. - Question 8 of 10
A CRAS is checking an infusion pump before a licensed nurse starts potassium chloride 20 mEq in 1,000 mL normal saline IV at 75 mL/hr continuous. The pump powers on, but the calibration sticker expired last month and the casing has a crack. What is the most appropriate next step?
Correct: C follows readiness checks: power alone is insufficient; expired calibration and physical damage can affect safe delivery, especially with potassium-containing IV fluids. B is tempting because cleanliness and power are required, but it ignores calibration and damage. D is tempting because order matching is important, but it does not resolve unsafe equipment. C is tempting as a workaround, but damaged equipment should not be patched for use. CRAS-level action is to remove from service, document, and notify/escalate according to policy.
- Question 9 of 10
A CRAS candidate is supporting a pharmacist-verified medication delivery for cefazolin 2 g IV every 8 hours. The room sign states: Contact Precautions—gown and gloves before entry; use dedicated equipment; clean hands before leaving. Under protocol, which workflow best matches the posted isolation category?
C is correct: contact precautions require gown and gloves for room entry and careful hand hygiene; the CRAS role is to follow signage and policy, not diagnose. A confuses droplet precautions with contact precautions. D applies airborne workflow, which is not posted. B ignores required PPE; urgency does not remove isolation requirements unless policy directs escalation.
NOTICE the posted category; SAY if PPE or delivery steps are unclear; MONITOR documentation for category alignment; HOLD/CLARIFY/ESCALATE if signage conflicts with orders or supplies are unavailable.
- Question 10 of 10
Under pharmacist-supervised protocol, a CRAS candidate is setting up materials for an order: apixaban 5 mg by mouth twice daily for nonvalvular atrial fibrillation. The profile shows age 82 years, weight 58 kg, serum creatinine 1.6 mg/dL, and ketoconazole 400 mg by mouth daily. Before preparing the medication, which next step best fits safe preparation and set-up?
Preparation checkpoint
A is correct: apixaban exposure can increase with renal impairment and strong CYP3A4/P-gp inhibitors; age, weight, and creatinine also trigger dose-review criteria. A CRAS candidate should gather facts and escalate, not alter therapy. D is tempting because it matches the order, but ignores interaction and dose flags. C is tempting because 2.5 mg is a labeled reduced dose, but independently changing the order exceeds role and still needs interaction review. B is tempting as same-class anticoagulation, but substitution is unauthorized and rivaroxaban also has renal/interaction concerns.
Pharmacist Action: NOTICE age/weight/SCr/ketoconazole; SAY “order needs review”; MONITOR bleeding and renal data per protocol; HOLD/CLARIFY/ESCALATE before preparation.
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